Long term (possibly lifelong) oral anticoagulation is the optimum prophylactic treatment for recurrent thrombosis and appears to be more effective than antiaggregants.18,19 Nevertheless, the recommended therapeutic international normalised ratio (INR) remains controversial. While awaiting these results, we recommend that an INR ranging between 2.5 and 3.5 is maintained.19The prevalence of pulmonary hypertension in APS associated with SLE and the primary APS has been estimated to be between 1.8% and 3.5%, respectively.21 The development of pulmonary hypertension in APS may result…